Focus on knowledge creation
Without ideas there is nothing to manageMarch 2021
The eTRANSAFE project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives. Pognan F, Steger‐Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K, Callegaro G, Capella‐Gutierrez S, Centeno E, Corvi J, Drew P, Drewe WC, Fernández JM, Furlong LI, Guney E, Kors JA, Mayer MA, Pastor M, Piñero J, Ramírez‐Anguita JM, Ronzano F, Rowell P, Saüch‐Pitarch J, Valencia A, van de Water B, van der Lei J, van Mulligen E and Sanz F.
Pharmaceuticals
Knwoledge managementData miningDrug toxicityDrug safetyData sharing
February 2021
Guidelines for FAIR Sharing of Preclinical Safety and Off-Target Pharmacology Data.
Briggs K, Bosc N, Camara T, Díaz C, Drew P, Drewe WC, Kors J, van Mulligen E, Pastor M, Pognan F, Quintana JR, Sarntivijai S, Steger-Hartmann T.
ALTEX
PreclinicalData sharingOff-target pharmacologyFAIR
November 2019
Real-world evidence in Alzheimer’s disease: The ROADMAP Data Cube.
Janssen O, Vos SJB, Garcia-Negredo G, Tochel C, Gustavsson A, Smith M, Ly A, Nelson M, Baldwin H, Sudlow C, Bexelius C, Jindra C, Vaci N, Bauermeister S, Gallacher J, Ponjoan A, Dufoil C, Garre-Olmo J, Pedersen L, Skoog I, Hottgenroth A, Jelle-Visser P, van der Lei J, Díaz C.
Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association
AlzheimerData sharingRWEEHR
January 2019
Challenges for Optimizing Real-World Evidence in Alzheimer’s Disease: The ROADMAP Project.
Gallacher J, de Reydet de Vulpillieres F, Amzal B, Angehrn Z, Bexelius C, Bintener C, Bouvy JC, Campo L, Díaz C, Georges J, Gray A, Hottgenroth A, Jonsson P, Mittelstadt B, Potashman MH, Reed C, Sudlow C, Thompson R, Tockhorn-Heidenreich A, Turner A, van der Lei J, Jelle Visser P. Journal of Alzheimer’s Disease
AlzheimerData sharingRWEEHR
April 2018
A methodology for fine-grained access control in exposing biomedical data.
Trifan A, van der Lei J, Díaz C, Oliveira JL.
Studies in health technologies and informatics
Data exposureData privacyData sharing
October 2017
Legacy data sharing to improve drug safety assessment: the eTOX project.
Sanz F, Pognan F, Steger-Hartmann T, Díaz C, eTOX, Cases M, et al.
Nature Reviews Drug Discovery
Drug toxicityData sharing
May 2017
Inmunization in pregnancy clinical research in low -and middle- income countries- Study design, regulatory and safety considerations.
Kochhar S, Bonhoeffer J, Jones CE, Muñoz FM, Honrado A, Bauwens J, Sobanjo-ter Meulen A, Hirschfeld S.
Vaccine
Clinical trialsVaccination ImmunizationPregnancyInfectious diseases
June 2016
Making sense of big data in health research: Towards an EU action plan.
Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, et al.
Genome Medicine
Big dataHealth research Medical informatics
October 2016
Global alignment of immunization safety assessment in pregnancy – The GAIA project.
Bonhoeffer J, Kochhar S, Hirschfeld S, Heath PT, Jones CE, Bauwens J, Honrado A, Heininger U, Muñoz FM, Eckert L, Steinhoff M, Black S, Padula M, Sturkenboom M, Buttery J, Pless R, Zuber P for the GAIA project participants.
Vaccine
Clinical trialsVaccinationImmunizationPregnancyInfectious diseases
December 2014
Guia de gestió projectes Horizon2020 (Guide for managing Horizon 2020 projects).
Honrado A, Molero E, Díaz C.
ACCIÓ-Agència per la Competitivitat de l’Empresa (Generalitat de Catalunya)
European projectsManagement Horizon2020
December 2013
Gathering and Exploring Scientific Knowledge in Pharmacovigilance.
Lopes P, Nunes T, Campos D, Furlong LI, Bauer-Mehren A, Sanz F, Carrascosa MC, Mestres J, Kors J, Singh B, van Mulligen E, Van der Lei J, Diallo G, Avillach P, Ahlberg E, Boyer S, Díaz C, Oliveira JL.
Public Library of Science (PLOS ONE)
PharmacovigilanceADR Data mining
December 2012
The EU-ADR Web Platform: Delivering advanced pharmacovigilance tools.
Oliveira JL, Lopes P, Nunes T, Campos D, Boyer S, Ahlberg E, van Mulligen EM, Kors JA, Singh B, Furlong LI, Sanz F, Bauer-Mehren A, Carrascosa MC, Mestres J, Avillach P, Diallo G, Díaz C, van der Lei J.
Pharmacoepidemiology and Drug Safety
PharmacovigilanceEHR ADR
May 2012
Knowledge engineering for health: a new discipline required to bridge the “ICT gap” between research and healthcare.
Beck T, Gollapudi S, Brunak S, Graf N, Lemke HU, Dash D, Buchan I, Díaz C, Sanz F, Brookes AJ.
Human Mutation
Knowledge engineeringVPH I4Health
February 2012
Electronic healthcare databases for active drug safety surveillance: is there enough leverage?
Coloma PM, Trifirò G, Schuemie MJ, Gini R, Hering R, Hippisley-Cox J, Mazzaglia G, Picelli G, Corrao G, Pedersen L, van der Lei J, Sturkenboom M, on behalf of the EU-ADR consortium.
Pharmacoepidemiology and Drug Safety
EHRDrug safetyDatabasesPharmacovigilance
January 2012
Automating classification of free-text electronic health records for epidemiological studies.
Schuemie MJ, Sen E, ‘t Jong GW, van Soest EM, Sturkenboom MC, Kors JA.
Pharmacoepidemiology and drug safety
EHRMachine learningData mining
May 2011
An Informatics Project and Online ‘‘Knowledge Centre’’ Supporting Modern Genotype-to-Phenotype Research.
Webb AJ, Thorisson GA, Brookes AJ, on behalf of the GEN2PHEN Consortium.
Human mutation
GenotypePhenotypeComputational biology
January 2011
Combining electronic healthcare databases in Europe to allow for large-scale drug safety monitoring: the EU-ADR Project.
Coloma P, Schuemie MJ, Trifirò G, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Giaquinto C, Corrao G, Pedersen L, van der Lei J, Sturkenboom M, on behalf of the EU-ADR Consortium.
Pharmacoepidemiology and Drug Safety
EHRDrug safetyDatabases
July 2010
In silico prediction of in vivo toxicity – the first steps of the e-Tox consortium.
Steger-Hartmann T, Pognan F, Sanz F, Díaz C, Sutter A, Pastor M.
Toxicology Letters
In vivoIn silicoDrug toxicity
March 2010
XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments.
Swertz MA, van der Velde KJ, Tesson BM, Scheltema RA, Arends D, Vera G, Alberts R, Dijkstra M, Schofield P, Schughart K, Hancock JM, Smedley D, Wolstencroft K, Goble C, de Brock EO, Jones AR, Parkinson HE, members of the Coordination of Mouse Informatics Resources (CASIMIR), Genotype-To-Phenotype (GEN2PHEN) Consortiums, Jansen RC.
Genome Biology
GenomicGeneticGenetic Association studiesGenotypePhenotype
December 2009
Data mining on electronic health record databases for signal detection in pharmacovigilance: which events to monitor?
Trifirò G, Pariente A, Coloma PM, Kors JA, Polimeni G, Miremont-Salamé G, Catania MA, Salvo F, David A, Moore N, Caputi AP, Sturkenboom M, Molokhia M, Hippisley-Cox J, Díaz C, van der Lei J, Fourrier-Reglat A, EU-ADR group.C.
Pharmacoepidemiology and Drug Safety
EHRDrug toxicityData mining
September 2009
In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach.
Steger-Hartmann T, Pognan F, Sanz F, Diaz C.
Toxicology Letters
In vivoIn silicoDrug toxicity
September 2009
The EU-ADR Project: Preliminary Results and Perspective.
Trifirò G, Fourrier-Reglat A, Sturkenboom MC, Díaz C, Van Der Lei J., EU-ADR Group.
Studies in health technologies and informatics
EHRDrug toxocityData mining
April 2009
Planning the Human Variome Project: The Spain Report.
Kaput J, Cotton RGH, Hardman L, Al Aqeel AI, Al-Aama JY, Al-Mulla F, et al.
Human Mutation
GenotypePhenotypePolymorphism
March 2008
Training Multidisciplinary Biomedical Informatics Students: Three Years of Experience.
van Mulligen EM, Cases M, Hettne K, Molero E, Weeber M, Robertson KA, Olivia B, de la Calle G, Maojo V.
Journal of the American Medical Informatics Association (JAMIA)
Medical informationData collectionEducation
Education and research in INFOBIOMED, the European Network of Excellence in Biomedical Informatics.De la Calle G, van Mulligen EM, Molero E, Perez-Rey D, Martín L, Crespo J, Maojo V.
AMIA: Annual Symposium Proceedings
Medical informationEducationGenomics
2005
INFOBIOMED: European Network of Excellence on Biomedical Informatics to Support Individualised Healthcare.
Maojo V, de la Calle G, Martín-Sánchez F, Díaz C, Sanz F.
AMIA: Annual Symposium Proceedings
Medical informaticsMicrobiologyPilot projects
2005
The INFOBIOMED network of excellence: developments for facilitating training and mobility.
de la Calle G, Benito M, Moreno JL, Molero E.
Proceeding ISBMDA’05
Mobility Brokerage serviceBioinformaticsStatistics
January 2004
Biomedical Informatics: From Past Experiences to the Infobiomed Network of Excellence.
Maojo V, Martin-Sanchez F, Barreiro JM, Díaz C, Sanz F.
Lecture Notes in Computer Science
Medical informationBioinformatics
November 2002
LINK3D: secure linking of organisations involved in distributed drug discovery.
Díaz C, Blat J, González A, Herráiz C, Laurie B, Molero E, Palmer JLS, Pastor M, Patak A, Ramírez A, Sanz F, Soto D and the LINK3D Consortium.
Challenges and Achievements in E-business and E-work
Computer simulationDrug discovery
November 2002
Distant collaboration in drug discovery: the LINK3D project.
Pastor M, Benedetti P, Carotti A, Carrieri A, Díaz C, et al. LINK3D Consortium.
Journal of computer-aided molecular design
Computer simulationDrug design
September 2000
Information technology in community pharmacies for supporting responsible self-medication.
Sanz F, Silveira C, Díaz C, Alonso A, Loza MI, et al.
American Journal of Health-System Pharmacy
Community pharmacySelf-medicationStatistics
January 2000
New technologies for the marketing and sale of medicines on the Internet and television networks. Final Study.
Sanz F, Gaedt K, Alonso A, Díaz C.
European Parliament DG Research (Directorate A) The STOA Programme
Medical informationEducationGenomicsData collection
• University degree in Political and Administration Sciences, Universitat Pompeu Fabra.
• Bachelor’s Degree in Communication from Instituto Tecnológico y de Estudios Superiores de Monterrey and in Journalism from Universidad Nacional Autónoma de México.
• University degree in Political Science and International Relations, Universidad Nacional de Rosario.
• PhD in Psychology, University of Edinburgh.
• University degree in Nursing, Universitat Autònoma de Barcelona.
• University double degree in Law & Political Sciences, Universidad Autónoma de Madrid.
• University degree in Industrial Engineering, Universidad Tecnológica Nacional.
• University degree in Telecommunication Engineering, Universidad Politécnica de Madrid.
• University degree in Business Administration, University of Barcelona.
• Ph.D. in Molecular Toxicology, University of Colorado Boulder.
• B.A. in Economics with Honors and Distinction from Stanford University.
• University degree in Tourism, Universitat de Barcelona.
• University degree in Advertising and Public Relationships, Universitat Autònoma de Barcelona.
• Ph.D. in Psychology and Neuroscience, Universidad Complutense de Madrid.
• University degree in Psychology, Universitat Autònoma de Barcelona.
• University degree in Social Sciences, Universidad de Vigo.
• University degree in Economy and Business Administration (Extraordinary Award), Universitat Autònoma de Barcelona.